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Monitoring tryptophan metabolism in chronic immune activation

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Renal interstitial fibrosis (RIF), a hallmark of different types of progressive CKD, is characterized by the deposition of excessive amounts of extracellular matrix (ECM) components (such as fibronectin and collagen), the accumulation of fibroblasts and the loss of renal tubular cells 5

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In recent years, unsupervised learning has proven particularly advantageous for handling large-scale datasets, with significant applications in fields such as image processing and natural language processing [26, 27]